Covid Update 4/17/20 | COVID 19 Information Page

Let start of the day with the headline and corresponding market share jump for Gilead – https://www.statnews.com/2020/04/16/early-peek-at-data-on-gilead-coronavirus-drug-suggests-patients-are-responding-to-treatment/

As noted in yesterday report on HCQ big complaint was the lack of no neutral control group “with no neutral control group for comparison, there is no conclusive proof that patients recover because of his treatment. As a result, it has not been authorised for use except in certain conditions in hospitals.” – well look at the Gilead article near the bottom – “The lack of a control arm in the study could make interpreting the results more challenging.” Strange shouldn’t it also get the same beat down then? Washington Post headlines below – it would suck if we are playing politics or worse yet economic maximization.

What is involved in a neutral group – well from what I surmise you would have to volunteer to a 50% chance you will not get treatment – hmmm who would bet on those odds with this virus?

Did some quick math HCQ dosage less than <$1 (multiple manufacturers) Remdesivir pill ~$1000 (1 manufacturer) – it better be 1000X more effective!

HCQ negative report – which actually highlights some reason the HCQ looks bad – its effectiveness is not designed for after inflammation – https://www.medrxiv.org/content/10.1101/2020.04.10.20060699v1.full.pdf

I am not a HCQ advocate per say but the mechanism on how it engages with better absorption to zinc makes sense to me. Clearly like any drugs you need to balance the side-effects with what you expect to get from the drug – hence the doctor role https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182877/

Value of Zinc – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277319/

Another treatment approach – also makes sense it terms of disinfection – I use a ozone generator to disinfect and remove odor (USE WITH CAUTION) – https://www.ptcommunity.com/wire/texas-right-know-calls-us-consider-covid-19-ozone-therapy-after-it-shows-promise-italy

Ozone paper – 2011 – noted Nikola Tesla was a proponent – he patented the first ozone generator in the US – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312702/

Another vitamin C supported reference – https://www.click2houston.com/health/2020/04/17/local-hospital-using-experimental-drug-treatment-in-hopes-of-saving-lives-of-covid-19-patients/?

BTW also <$1 a dose….

More papers supporting the issue of our lifestyle. Given we are forced to isolate perhaps forcing a diet would be less restrictive? Make the grocery story only have unprocessed foods and/or limited process foods. The sad but funny thing is when I go grocery shopping – the vegan frozen items are available – kale/spinach always available….we have some personal accountability….would I like the chocolate pie – for sure – but I know its not good for me…. https://www.europeanscientist.com/en/article-of-the-week/covid-19-and-the-elephant-in-the-room/

“in 2009 61% of patients admitted to hospital in California that died from H1N1 Influenza A were obese, which was 2.2 times more than the prevalence of obesity within the state population.”

“obese adults shed influenza A virus 42% longer than non-obese individuals suggesting an additional role in transmission.”

“In Nature states that “patients with type 2 diabetes and metabolic syndrome might have to up 10 times greater risk of death when they contract COVID-19” and has called for mandatory glucose and metabolic control of type 2 diabetes patients to improve outcomes.”

“Public Health England have said now is the best time to quit smoking, citing research from China concluding that smokers were 14 times more likely to get severe disease after contracting COVID-19.”

“25-50% of those with type 2 diabetes can significantly improve glycaemic control, blood pressure and send their condition into remission from a variety of interventions including a low refined carbohydrate diet (without needing to count calories) within weeks to months respectively.”

While you are quarantined watch Forks Over Knives, Fat Sick and Nearly Dead

Spent so much time figuring this big jump in US death 4591 – hence late release!….70% all in NY – got to be some massive revision. Some sources don’t have this number yet – but John Hopkins does.