Dr. Ing was gracious enough to respond to my email and gave me their treatment plan which as noted involved 128/217 positive – with only 16 with symptoms – 8 medically evacuated – 4 intubation and ventilation – 1 death.
“Mildly symptomatic patients were just managed with paracetamol
More symptomatic patients including dyspnoea were also managed with oral Azithromycin. Some required supplemental oxygen but were not evacuated.
Medically evacuated passengers were managed with Remdesivir, Hydroxychloroquine and Azithromycin; and those intubated were managed in the prone position.
Regards
Alvin Ing”
FYI Paracetamol – Acetaminophen (Tylenol).
This was an amazing outcome compared to all the other outcomes. Fatality rate 0.8% – Death per capita 0.5%.
I have asked for the demographics of those above and will update it when I get it.
HCQ is going to be reviewed in history books in the future not sure on the conclusions just yet but no doubt this was mismanaged and politicized for no good reason. The line in the sand is drawn now with the WHO abandoning HCQ and many of the media bashing HCQ. The positive is there are countries (e.g. Saudi Arabia, India (see below) )and doctors who will continue the drug and so time will tell who was right.
“The Indian Council of Medical Research (ICMR), the country’s apex body in the field, has found that consuming the drug hydroxychloroquine reduces the chances of getting infected with Covid-19.”
““amongst healthcare workers involved in Covid-19 care, those on HCQ prophylaxis were less likely to develop SARS-CoV-2 infection, compared to those who were not on it”.
“National Institute of Virology in Pune has found in laboratory testing that HCQ reduces the viral load.”
“observational study was conducted among 334 healthcare workers at the country’s largest public hospital, New Delhi’s All India Institute of Medical Sciences (AIIMS). The 248 workers who took HCQ as preventive drug for an average of six weeks had lower incidence of the infection than those not taking the pill.”
“With available evidence for its safety and beneficial effect as a prophylactic drug against SARS-CoV-2 during the earlier recommended 8 weeks period, the experts further recommended for its use beyond 8 weeks on weekly dosage with strict monitoring of clinical and ECG parameters, which would also ensure that the therapy is given under supervision”
“the final results of the studies (HCQ prophylaxis among 1,323 healthcare workers), the ICMR found mild adverse effects such as nausea in 8.9 per cent workers, abdominal pain in 7.3 per cent, vomiting in 1.5 per cent, low blood sugar (hypoglycaemia) in 1.7 per cent and cardio-vascular effects in 1.9 per cent.
The advisory states the drug should be discontinued if it causes the “rare” side effects related to the heart, such as cardiomyopathy, a disease which makes it harder for heart to pump blood to the entire body, and heart-rate disorders.
The advisory mentions that HCQ, in rare cases, can cause visual disturbance, including “blurring of vision, which is usually self-limiting and improves on discontinuation of the drug”.
ICMR has clarified that “for the above cited reasons — heart and vision — the drug has to be given under strict medical supervision with an informed consent”.
Once again a small per cent with heart issues (1.9%) – however they are rational in not sacrificing the remaining 98% for the small amount of risk which can be mitigated through supervision. NOTE the LANCET study was only 3.7% and WHO decided to pull the study. THE OVERALL side effect is minimal – highest was nausea 8.9% – hence HCQ has been used for decades to treat malaria! HCQ risk is understood quite well. The rewards is not so clear – but even a placebo effect could be worth it given the minimal risk.
NY retrospective observational study HCQ and zinc sulfate – https://www.medrxiv.org/content/10.1101/2020.05.02.20080036v1
“After adjusting for the time at which zinc sulfate was added to our protocol, an increased frequency of being discharged home (OR 1.53, 95% CI 1.12-2.09) reduction in mortality or transfer to hospice remained significant (OR 0.449, 95% CI 0.271-0.744). Conclusion: This study provides the first in vivo evidence that zinc sulfate in combination with hydroxychloroquine may play a role in therapeutic management for COVID-19.”
“No funding was provided for this work.”
The not so clean side of quarantine and lockdown and beyond just the economy – which is more apparent in countries who standard of living is much lower. Sacrificing the many for the few who could die from covid is a real math equation that needs to be factored in all policy decision. https://www.livemint.com/news/india/how-covid-19-response-disrupted-health-services-in-rural-india-11587713155817.html
“India could find itself in an acute health crisis over the next few months and the direct cause of it will not be the SARS-CoV-2 virus. Hundreds of thousands of children might already have missed vital immunizations, shows a Mint analysis of the latest health ministry data. Thousands of adults may have missed potentially life-saving medical treatment as the novel coronavirus epidemic spread and a lockdown came into force.”
“the number of unattended home births is likely to have gone up.”
“At least 100,000 children did not receive their BCG vaccination, which can provide some protection against tuberculosis (TB), and another 200,000 missed each dose of the pentavalent vaccine, which provides some protection against meningitis, pneumonia, whooping cough, tetanus, hepatitis B and diphtheria, and the rotavirus vaccine, which prevents diarrhoea-causing rotavirus infections, in March, suggests the analysis.”
“At least 350,000 fewer people received outpatient treatment for diabetes, 150,000 fewer people received outpatient treatment for mental illness and nearly 100,000 fewer people received outpatient cancer treatment in March 2020 as compared to March 2019.”
““A person who misses her tuberculosis or cancer medication today might not die this month but some months down the line. We should really be pushing for all-cause mortality data for the whole year ahead to understand the impact of this virus and lockdown on broader public health. You don’t want a situation where you save 300,000 deaths from covid and then 1.2 million people die of other causes," said Jain of Jan Swasthya Sahyog.”
“The analysis of the latest NHM numbers suggests that a serious public health crisis is already brewing, with the potential to erase gains made against a number of diseases over decades.”
Brazil continues to lead confirmation 26928 with 1124 deaths. US death 1193. NY has tested almost 10% of the population – so far nearly 2% of the population tested positive.
New Jersey leading the way for the US with 122 deaths.
County view allows one to dive into the real issues. Not like Minnesota needs any more issues but Hennepin county is not looking to good on the covid front – https://www.kare11.com/article/news/health/coronavirus/live-updates-covid-19-developments-in-minnesota-and-wisconsin-5-11-2020/89-e8d97669-dd6a-42bb-b274-b4ae9cd6ecfd
“One third of the state’s confirmed cases are in Hennepin County, and Hennepin and Ramsey Counties combined make up 40% of the state’s total cases, MDH Commissioner Jan Malcolm said on the department’s daily briefing call Monday. About half of the new cases reported Monday were in those two counties, as well. Malcolm said seven counties have outbreaks in food processing plants, and those cases account for about a third of the new cases. Those outbreaks, she said, are beginning to level off.”
Once again it looks like our food system needs to be revisited.
Russia death per confirmed now over 1%. Russia and India now 10% of daily death.
Mexico looks to be moderating now – however India and Russia still accelerating.
