Covid 9/18/20

Yes its still 2020 – https://www.cnn.com/2020/09/17/health/michigan-eee-case-suspected-trnd/

“Not only are Michigan health officials dealing with the coronavirus, but they’re also trying to contain the spread of a rare mosquito-borne disease.

Authorities are urging people to stay indoors after dark and protect themselves from mosquito bites after a resident in Barry County was suspected of having Eastern Equine Encephalitis (EEE), a potentially deadly illness caused by the EEE virus.”

More indoors less ventilation more covid vs. more EEE?

Sputnik V results – https://www.hindustantimes.com/world-news/1-in-7-volunteers-for-sputnik-v-russia-s-covid-19-vaccine-report-side-effects-russian-minister/story-0skeCHrE1ys9gKroFbXiIP.html

“One in seven volunteers complained of side effects after being injected with Sputnik V, Russia’s experimental vaccine against the coronavirus disease (Covid-19), the country’s health minister has said.

Mikhail Murashko, the Russian health minister, said more than 300 out of the announced 40,000 volunteers have been vaccinated with Sputnik V so far, according to the state-run TASS news agency.”

““Approximately 14% have small complaints of weakness, muscle pain for 24 hours and an occasional increase in body temperature,” TASS quoted Murashko as saying on Wednesday, according to Moscow Times.

The minister said the symptoms after being injected with the anti-coronavirus vaccine “level off” by the next day. “The complications are described in the instructions and are predictable,” he said, according to TASS.”

“The Sputnik V has yet to complete large scale clinical trials but was approved by the Russian government last month, becoming the first Covid-19 vaccine to be cleared for human use anywhere in the world.”

“Sputnik V did not lead to side effects and triggered an adequate immune response in 76 volunteers according to phase 1/2 trial data published in The Lancet journal earlier this month. But the results have been disputed by some scientists, who have sought a review of the data, citing what they said were striking similarities between patients.”

“RDIF reiterated on Wednesday that the vaccine is safe. “The Sputnik V vaccine, which is based on well-studied human adenoviral vector platform with proven safety, is undergoing clinical trials for the Coronavirus pandemic. Deliveries could potentially begin in late 2020 subject to completion of successful trials and registration of the vaccine by regulatory authorities in India,” a statement said.”

More from India shows that the plasma treatment is not effective – https://www.the-scientist.com/news-opinion/indian-study-shows-no-survival-benefit-of-plasma-in-covid-19-67931

“the use of convalescent plasma therapy is in vogue globally. It involves the infusion of plasma from patients who have recovered from COVID-19 and thus carry protective antibodies into patients who are currently infected with the coronavirus. The US Food and Drug Administration (FDA) recently granted emergency use authorization (EUA) for its use, although the absence of randomized controlled trials (RCTs), the gold standard of scientific research, has led to skepticism about its effectiveness among experts.”

“Recently conducted by the Indian Council of Medical Research (ICMR), the apex medical research body in India, it is the first RCT for plasma in COVID-19 patients to be completed in the world. The study included 464 hospitalized, moderately ill COVID-19 patients—they were on supplemental oxygen but not critically ill with organ damage—across 39 medical centers between April 22 and July 14. The trial had two arms: an intervention arm, in which patients received two doses of 200 ml of convalescent plasma, 24 hours apart, along with standard of care, and a control arm that received standard of care alone.

The results, posted as a preprint on September 8 with a revision posted two days later, signal that the use of convalescent plasma in COVID-19 patients did not forestall progression to severe disease or mortality.”

“Despite the lack of survival benefit shown in the ICMR study, some positives gleaned from the trial include improved symptoms and oxygenation and faster viral clearance in patients in the intervention arm compared with the control arm.”

India back reporting leading at 1132 – US and Brazil both under 900

FL leads US at 147

Miami-Dade FL leads all counties at 22 – surrounding counties also around 20’s. LA county at 21

Big 4 counties view – LA CA and Miami Dade FL cant seem to trend down in deaths unlike Harris TX and Maricopa AZ. Almost 11.5% confirmed per capita in LA. 10.6% in Maricopa AZ

It would seem Covid is becoming unavoidable whether its for real or the testing sensitivities are high – the fact is lockdowns have not resulted in elimination – perhaps flatten the curve but the area under the curve (integral) will likely be the same over time.