Covid 12/16/20

Covid19mathblog.com

How in the world does it take this long to know this about such a common drug – Aspirin – https://www.medrxiv.org/content/10.1101/2020.12.13.20248147v1

“Among COVID-19 positive Veterans, preexisting aspirin prescription was associated with a statistically and clinically significant decrease in overall mortality at 14-days (OR 0.38, 95% CI 0.32-0.46) and at 30-days (OR 0.38, 95% CI 0.33-0.45), cutting the odds of mortality by more than half. Findings demonstrated that pre-diagnosis aspirin prescription was strongly associated with decreased mortality rates for Veterans diagnosed with COVID-19.”

Really – so this long to come up with this – sounds like blood is on someones hands – https://www.ama-assn.org/system/files/2020-10/nov20-handbook-addendum.pdf

“RESOLVED, That our American Medical Association rescind its statement calling for physicians

5 to stop prescribing hydroxychloroquine and chloroquine until sufficient evidence becomes

6 available to conclusively illustrate that the harm associated with use outweighs benefit early in

7 the disease course. Implying that such treatment is inappropriate contradicts AMA Policy

8 H-120.988, “Patient Access to Treatments Prescribed by Their Physicians,” that addresses off

9 label prescriptions as appropriate in the judgement of the prescribing physician (Directive to

10 Take Action); and be it further”

“RESOLVED, That our AMA reassure the patients whose physicians are prescribing

19 hydroxychloroquine and combination therapies for their early-stage COVID-19 diagnosis by

20 issuing an updated statement clarifying our support for a physician’s ability to prescribe an FDA21 approved medication for off label use, if it is in her/his best clinical judgement, with specific

22 reference to the use of hydroxychloroquine and combination therapies for the treatment of the

23 earliest stage of COVID-19 (Directive to Take Action); and be it further

24

25 RESOLVED, That our AMA take the actions necessary to require local pharmacies to fill valid

26 prescriptions that are issued by physicians and consistent with AMA principles articulated in

27 AMA Policy H-120.988, “Patient Access to Treatments Prescribed by Their Physicians,”

28 including working with the American Pharmacists Association and American Society of Health”

Finally some more test – this requires no lab – https://www.npr.org/sections/health-shots/2020/12/15/946692950/fda-authorizes-first-home-coronavirus-test-that-doesnt-require-a-prescription

“The new test is the first that people will be able to buy without a prescription at a local store and do entirely at home on their own. It takes about five minutes to collect the sample and produces results within 15 minutes.”

A slight caution on the vaccine – certainly if you don’t fall into the critical demographic probably best to wait a bit just to balance risk/reward – still very small percent and even smaller for longerterm impact – https://www.cnbc.com/2020/12/15/fda-staff-recommends-watching-for-bells-palsy-in-moderna-and-pfizer-vaccine-recipients.html

“The FDA said that there were four reported cases of Bell’s palsy among Moderna’s 30,000 trial participants, including three who got the vaccine.”

“Two of the cases of Bell’s palsy among Moderna’s vaccine group have since “resolved” while one was still ongoing at the time of the report, the FDA staff said. The vaccinated participants experienced the paralysis between 22 days and 32 days following inoculation, they said.”

Unfortunately back up to 3K deaths in US

CA leads in both confirmation and deaths

LA county driving most of CA issues

Something needs to be done in LA region if covid numbers to flat line

LA is astronomical