Covid 5/20/21

Covid19mathblog.com

New treatment drug available with high effectiveness – New Antiviral Drug Developed With 99.9 Per Cent Efficacy Against COVID-19 | The Weather Channel – Articles from The Weather Channel | weather.com

“The new antiviral approach used gene-silencing RNA technology called siRNA (small-interfering RNA) to attack the virus’ genome directly, which stops the virus from replicating. This approach also uses lipid nanoparticles designed at Griffith University and the City of Hope to deliver the siRNA to the lungs, the critical site of infection.

"Treatment with virus-specific siRNA reduces viral load by 99.9 per cent. These stealth nanoparticles can be delivered to a wide range of lung cells and silence viral genes," said co-lead researcher Nigel McMillan, Professor at Menzies Health Institute Queensland (MHIQ) at Griffith University.

When tested in SARS-Cov-2 infected mice the treatment with the therapy improved survival chances. Remarkably, in treated survivors, no virus could be detected in the lungs, the findings published in the journal Molecular Therapy, reported.

"This treatment is designed to work on all beta coronaviruses such as the original SARS virus (SARS-CoV-1) as well as SARS-CoV-2 and any new variants that may arise in the future because it targets ultra-conserved regions in the virus’ genome," added Kevin Morris, Professor and associate director of the Center for Gene Therapy at City of Hope.

Further, the researchers also showed that the nanoparticles are stable at 4°C for 12 months and at room temperature for greater than one month. This means that this agent could be used in low-resource settings to treat infected patients.”

Hmmm increase incidences in Singapore and Taiwan being discussed perhaps news is slowing down – look at graphs below – so small I had to use Log chart – no doubt an increase but coming from essentially zero – Covid-19: What went wrong in Singapore and Taiwan? – BBC News

“They’ve been hailed as virus success stories – places that have seen virtually zero or single-digit Covid cases since the start of the year.

But this month, Singapore and Taiwan have both seen a sudden and aggressive rise in cases – with Singapore logging 248 new cases just last week, and Taiwan 1,200 local infections.

Both places have gone into a heightened state of restrictions, limiting the size of social gatherings and closing schools.

By global standards, these numbers may seem small – but for these places, these figures would have been unthinkable just months ago. So what exactly went wrong?”

Personally there is overweight celebration as a result of vaccination. I have been anticipating May to be the end of the surge for Covid in the US for quite some time. The timing was impeccable as the weather got better. There is no coincidence that flu and colds also go away this time – AND those without vaccine. I do believe vaccine plays a role but not the to extent suggested. Naturally people are going out and exercising which also boost the immune system. Then the fact the coronavirus doesn’t encapsulate themselves in the heat is leaving them more vulnerable in the air. Hypothesis: Potentially A/C creates cold pockets initiating encapsulation allowing them to sustain themselves longer indoors. Potential to get a summer blip IF we don’t ventilate better and/or use devices to reduce the virus.

Still India leading….US is approaching 10% confirmed per capita

India confirmation taking a strong drop now….unfortunately not deaths

Given the US sample of 50 states….I suspect a typical society will get to 10% confirmed per capita – or significant levels of vaccinations would need to be done.

Hmm not sure why Lollapalooza going to be Chicago….still the top confirming county in the US

Vaccination has slowed down significantly in the US

Even the live free or die state still has decent vaccination levels