Covid 8/3/21

Covid19mathblog.com

I am sure somehow we can politicize this report given coming from a republican but I guess IF you have that attitude that anything they say is wrong you won’t agree a broken clock is right twice a day. Certainly there are decent questions brought up to the origin of covid-19 report – and likely pushes the odds that it was leaked from the lab. https://gop-foreignaffairs.house.gov/wp-content/uploads/2021/08/ORIGINS-OF-COVID-19-REPORT.pdf

“Based on the material collected and analyzed by the Committee Minority Staff, the preponderance of

evidence suggests SARS-CoV-2 was accidentally released from a Wuhan Institute of Virology

laboratory sometime prior to September 12, 2019. The virus, or the viral sequence that was

genetically manipulated, was likely collected in a cave in Yunnan province, PRC, between 2012 and

2015. Researchers at the WIV, officials within the CCP, and potentially American citizens directly

engaged in efforts to obfuscate information related to the origins of the virus and to suppress public

debate of a possible lab leak.”

“The sudden removal of the WIV’s virus and sample database in the middle of the night on

September 12, 2019 and without explanation;

Safety concerns expressed by top PRC scientists in 2019 and unusually scheduled maintenance at

the WIV;

Athletes at the Military World Games held in Wuhan in October 2019 who became sick with

symptoms similar to COVID-19 both while in Wuhan and also shortly after returning to their

home countries;

Satellite imagery of Wuhan in September and October 2019 that showed a significant uptick in

the number of people at local hospitals surrounding the WIV’s headquarters, coupled with an

unusually high number of patients with symptoms similar to COVID-19;

The installation of a People’s Liberation Army’s bioweapons expert as the head of the WIV’s

Biosafety Level 4 lab (BSL-4), possibly as early as late 2019; and

Actions by the Chinese Communist Party and scientists working at or affiliated with the WIV to

hide or coverup the type of research being conducted at there.”

“we have uncovered further evidence of how top scientists at the WIV and Dr. Peter

Daszak, an American scientist, furthered that cover-up. Their actions include bullying other scientists

who questioned whether the virus could have leaked from a lab; misleading the world about how a

virus can be modified without leaving a trace; and, in many, instances directly lying about the nature

of the research they were conducting, as well as the low-level safety protocols they were using for

that research.

These actions not only delayed an initial investigation into the possibility of a lab leak costing

valuable time, but provide further proof the virus likely leaked from the WIV”

“Given the WIV’s demonstrated history of conducting gain-of-function

experiments on coronaviruses, including genetically manipulating viruses specifically to make them

infectious to humans in BSL-2 labs, as well as their possession of one of the world’s largest

collections of coronaviruses, it is completely plausible that one or more researcher(s) was

accidentally infected and carried the virus out of the lab”

“The WIV was

conducting gain-of-function research on

coronaviruses and testing them against human

immune systems in the months leading up to the

emergence of SARS-CoV-2, however the scientific

community has claimed it is not possible it was

anything but a naturally occurring virus. But, as this

report lays out, we believe it is a viable hypothesis

that the virus could have been modified.”

“.

In sum, in the years leading up to the emergence of SARS-CoV-2, there was:

Unusual Features of SARS-CoV-2

Committee Minority Staff interviews with scientists and current and former U.S. government

officials raised several questions about the natural origins of SARS-CoV-2, including:

1. The highly infectious nature of SARS-CoV-2, which they consider as infectious as measles;

2. The lack of an identified intermediate host (found 4 months after the outbreak of SARS and 9

months after MERS); and

3. The highly efficient binding to human ACE2.

The highly contagious nature of SARS-CoV-2 has been a hot topic of conversation since the virus

began to spread around the world. Some scientists and other experts point to the incredibly high case

numbers as evidence that SARS-CoV-2 is inherently different from known natural betacoronaviruses.

For example, MERS first appeared in 2012 and has infected less than 4,000 people. SARS first

appeared in 2002 and infected less than 10,000. At the time of writing, less than two years from when

it has first appeared, SARS-CoV-2 has infected more than 196.4 million people.

SARS-CoV-2 also has a highly unusual affinity for binding to human ACE2 receptors over other

hosts. In February 2020, American researchers examined this issue closely. They found that SARSCoV-2’s spike protein “binds at least 10 times more tightly than the corresponding spike protein of

severe acute respiratory syndrome (SARS)–CoV to their common host cell receptor.” In other words,

SARS-CoV-2 binds more than 10 times more tightly to human ACE2 than the virus that causes

SARS. The researchers found this likely explains why the virus is so contagious.

Given the above, it is self-evident that Shi and her colleagues, with fund”

“The paper stated these viruses were “indistinguishable from wild type,” meaning that it is impossible

to tell they were synthetically created.

Baric himself confirmed this interpretation in a September 2020 interview, where he stated, “You can

engineer a virus without leaving any trace. The answers you are looking for, however, can only be

found in the archives of the Wuhan laboratory.” Referring to chimeric viruses he generated in 2015

with WIV researchers, Baric said his team intentionally left signature mutations to show that it was

genetically engineered. “Otherwise there is no way to distinguish a natural virus from one made in

the laboratory.”

Shi and Baric have collaborated on multiple papers regarding coronaviruses. The most recent of

which was in May 2020, when they joined other researchers in publishing “Pathogenesis of SARSCoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2.” One year later,

Baric signed onto a May 14, 2021, letter published in Science which argued that the lab leak

theory must be taken seriously and should be fully evaluated”

“The PRC’s efforts to obfuscate the origins of COVID-19 were not limited to destroying samples and

silencing doctors, but featured a sustained disinformation campaign as well. As discussed in our

previous report, Lijian Zhao, an official within the PRC’s Foreign Ministry, shared an article on

Twitter that claimed the virus was brought to the PRC by the U.S. military. The article was from the

Global Times research.ca, a website that pushes pro-Putin propaganda and has reported ties to

Russian state media. His tweet was amplified by the Chinese Embassy in South Africa.”

“It should also be noted that Daszak was the only representative of the United States on the WHOChina Joint Study team in early 2021. The United States put forth a list of experts to be considered,

none of whom were chosen. Daszak was not on that list but was nevertheless selected and approved

by the CCP”

“Peter Daszak has taken several additional concerning actions in regard to the origins of COVID-19,

including inexplicably lying about the work conducted by EcoHealth Alliance in the months

following the emergence of SARS-CoV-2. In an August 21, 2020, interview with Nature, after the

NIH suspended the grants he was using to fund research at the WIV, Daszak claimed “The grant isn’t

used to fund work on SARS-CoV-2. Our organization has not actually published any data on SARSCoV-2.” This is despite the fact that four days later Nature Communications published “Origin and

cross-species transmission of bat coronaviruses in China.” Daszak, Shi, Hu, and Wang are all listed

as authors, with Shi and Daszak both being listed as corresponding authors”

Another success note for Ivermectin – https://m.jpost.com/health-science/israeli-scientist-says-covid-19-could-be-treated-for-under-1day-675612/amp?__twitter_impression=true

“Ivermectin, a drug used to fight parasites in third-world countries, could help reduce the length of infection for people who contract coronavirus for less than a $1 a day, according to recent research by Sheba Medical Center in Tel Hashomer.

Prof. Eli Schwartz, founder of the Center for Travel Medicine and Tropical Disease at Sheba, conducted a randomized, controlled, double-blinded trial from May 15, 2020, through the end of January 2021 to evaluate the effectiveness of ivermectin in reducing viral shedding among nonhospitalized patients with mild to moderate COVID-19.”

“In Schwartz’s study, some 89 eligible volunteers over the age of 18 who were diagnosed with coronavirus and staying in state-run COVID-19 hotels were divided into two groups: 50% received ivermectin, and 50% received a placebo, according to their weight. They were given the pills for three days in a row, an hour before a meal.

The volunteers were tested using a standard nasopharyngeal swab PCR test with the goal of evaluating whether there was a reduction in viral load by the sixth day – the third day after termination of the treatment. They were swabbed every two days.

Nearly 72% of volunteers treated with ivermectin tested negative for the virus by day six. In contrast, only 50% of those who received the placebo tested negative.

IN ADDITION, the study looked at culture viability, meaning how infectious the patients were, and found that only 13% of ivermectin patients were infectious after six days, compared with 50% of the placebo group – almost four times as many.

“Our study shows first and foremost that ivermectin has antiviral activity,” Schwartz said. “It also shows that there is almost a 100% chance that a person will be noninfectious in four to six days, which could lead to shortening isolation time for these people. This could have a huge economic and social impact.””

https://www.medrxiv.org/content/10.1101/2021.05.31.21258081v1

“On day 6, 34 out of 47 (72%) patients in the ivermectin arm reached the endpoint, compared to 21/ 42 (50%) in the placebo arm (OR 2·62; 95% CI: 1·09-6·31). In a multivariable logistic-regression model, the odds of a negative test at day 6 was 2.62 time higher in the ivermectin group (95% CI: 1·06–6·45). Cultures at days 2 to 6 were positive in 3/23 (13·0%) of ivermectin samples vs. 14/29 (48·2%) in the placebo group (p=0·008).

Conclusions There were significantly lower viral loads and viable cultures in the ivermectin group, which could lead to shortening isolation time in these patients.”

Another potential treatment for Covid – https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202001792R

“We have identified potential therapeutic targets of berberine against both SARS and COVID-19 using computational modeling. The most prominent targets for berberine relevant to host immune response include NF-κB and MAPKs, which are important proteins regulating the cytokine storm, and CASPs and BAX, which are relevant targets in preventing tissue damage via suppressing cell death signaling pathways. Besides balancing host immune responses, our molecular docking analysis identifies berberine as a potential antagonist of host receptor for viral entry, such as ACE2 and TMPSS2, and may inhibit virus proteins. Furthermore, as the first step to validate our computational modeling results, we for the first time demonstrate that berberine significantly reduced viral replication, suppressed viral entry host receptor ACE2 and TMPSS2, and decreased inflammatory markers including IL-6, IL-8, IL-1α, and CCL2 in SARS-CoV-2 infected lung epithelial cells. Given that berberine/NIT-X exhibits high oral bioavailability and has previously been shown to have in vivo immunomodulatory effects and suppression of hyper-mast cells activation, berberine/NIT-X has the potential to become a promising, orally active therapeutic against COVID-19 and SARS. However, direct evidence of berberine antagonist to ACE2, TMPRSS2 protein, and binding activities with these receptors and other targets have not been elucidated in this study and will be further investigated in our future research.”

Perhaps instead of lockdown and mask and vaccine mandates – perhaps lets just ban sugar, carbs, seed oil and see what happens 1 month later….. https://www.israel21c.org/diet-the-biggest-covid-risk-factor-that-nobody-talks-about/

Covid has been very bad for the western world – its like designed to hurt them over the other parts of the world – else they are underreporting which is a possibility. Norway is the outlier. Even Australia and NZ are low and relate more to Asian countries than the west.

Canada Cancer still leads deaths

Japan so much other things to worry about – even flu more of an issue than covid

S. Korea similar to even less of an issue

Australia lockdown perhaps is overblown given how low deaths from Covid

Thailand 2020 covid deaths don’t even show up

S. Africa Aids is still more of an issue

India large deaths still not as high as flu death rates

Germany only Cancer had more deaths

Turkey had a few more categories in front of covid

Saudi Arabia had more issues with flu

Norway flu was more of an issue

Netherlands only Cancer in front

New Zealand covid deaths not even in the top 20

Sweden not faring well….

Indonesia deaths are starting to add up as compared to 2020 – now greater than flu

Indonesia continues to lead the death boards

Cuba is showing an alarming rate of confirmation

FL and TX leads the US

On a per capita basis FL and LA are the hotspots – not clear low vaccinations leading to high confirmations

Confirmation absolute view is much higher than usual – lots of counties showing up in the 250+ Death hot spots still low