Covid 2/14/21 | COVID 19 Information Page

Covid19mathblog.com

Happy Valentine’s Day!

If we find a low cost effective treatment would you need a vaccine?

The love for Vitamin D is supported in the following paper – once again it is not a common available form of vitamin D for some reason – https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3771318

“Findings: ICU assistance was required by 110 (11.8%) participants. Out of 551 patients treated with calcifediol at admission, 30 (5.4%) required ICU, compared to 80 out of 379 controls (21.1%; p<0.0001). Logistic regression of calcifediol treatment on ICU admission, adjusted by age, gender, linearized 25(OH)D levels at baseline, and comorbidities showed that treated patients had a reduced risk to require ICU (RR 0.18 [95% CI 0.11;0.29]). Baseline 25(OH)D levels inversely correlated with the risk of ICU admission (RR 0.53 [95% CI 0.35;0.80]). Overall mortality was 10%. In the Intention-to-treat analysis, 36 (6.5%) out of 551 patients treated with calcifediol at admission died compared to 57 patients (15%) out of 379 controls (p=0.001). Adjusted results showed a reduced mortality for more of 60%. Higher baseline 25(OH)D levels were significantly associated with decreased mortality (RR 0.40 [95% CI 0.24;0.67]). Age and obesity were also predictors of mortality.

Interpretation: In patients hospitalized with COVID-19, calcifediol treatment at the time of hospitalization significantly reduced ICU admission and mortality.”

Another potential treatment yielding good results focused on suppressing the immune system from overreacting – it would also seem that the virus itself would want to do this as why would it want its host to die? – https://www.cityam.com/new-immune-drug-seen-as-possible-covid-19-cure-as-90-per-cent-of-treated-patients-fully-recover/

“Medics in Israel have been given the go-ahead for a third trial of a relatively new drug after successfully testing the treatment on a number of severely ill Covid-19 patients, of which 90 per cent fully recovered within a week, according to multiple media reports.

The drug, Allocetra, aims to slow or halt an extreme overreaction of the immune system, a so-called cytokine storm. It often follows a coronavirus infection and is believed to be responsible for many Covid-related deaths as it regularly leads to organ failure.

Allocetra, first developed at the Research Center for Rheumatology and Internal Medicine (CRIM) at Jerusalem’s Hadassah Medical Centre, was tested on 21 patients, of which 19 showed significant improvements within days and were discharged after a week, according to Israel’s Channel13 in Israel.”

It is a big number for a weekend US 3.6K