Covid 7/14/20

Being non-geneticist I think this article does a pretty good job of describing virus evolution and their theory on that the virus did not come from a lab – also lots of good facts in the article- https://thenextweb.com/syndication/2020/07/14/scientists-know-coronavirus-came-from-bats-not-a-lab-heres-how/

“An estimated 60% of known infectious diseases and 75% of all new, emerging, or re-emerging diseases in humans have animal origins. SARS-CoV-2 is the newest of seven coronaviruses found in humans, all of which came from animals, either from bats, mice or domestic animals. Bats were also the source of the viruses causing Ebola, rabies, Nipah and Hendra virus infections, Marburg virus disease, and strains of Influenza A virus. The genetic makeup or “genome” of SARS-CoV-2 has been sequenced and publicly shared thousands of times by scientists all over the world. If the virus had been genetically engineered in a lab there would be signs of manipulation in the genome data. This would include evidence of an existing viral sequence as the backbone for the new virus, and obvious, targeted inserted (or deleted) genetic elements.

But no such evidence exists. It is very unlikely that any techniques used to genetically engineer the virus would not leave a genetic signature, like specific identifiable pieces of DNA code.”

“One of the key features that makes SARS-CoV-2 different from the other coronaviruses is a particular “spike” protein that binds well with another protein on the outside of human cells called ACE2. This enables the virus to hook into and infect a variety of human cells. However, other related coronaviruses do have similar features, providing evidence that they have evolved naturally rather than being artificially added in a lab.”

“It is also important to remember that around one in five of all mammal species on Earth are bats, with some found only in certain locations and others migrating across vast distances. This diversity and geographical spread makes it a challenge to identify which group of bats SARS-CoV-2 originally came from.”

Bad news confirmed – looks like the virus can infect the brain so not just a respiratory issue – https://onezero.medium.com/what-miniature-lab-grown-brains-reveal-about-the-effects-of-covid-19-e73b7c1b84e9

“Hartung and his team are using the brain organoids to better understand SARS-CoV-2, the virus that causes Covid-19. What they’ve found so far about the brain’s susceptibility to the virus is concerning: “It’s bad news adding to a pile of bad news,” Hartung tells OneZero.”

“What she found was that the virus could infect the mini brains and, 72 hours later, it began multiplying inside them, suggesting that human brain cells are susceptible to the virus.”

“Chinese researchers reported that about 36% of 214 Covid-19 patients at a Wuhan hospital had neurological symptoms in addition to respiratory ones. And a study published July 8 in the journal Brain found that neurological complications of Covid-19 can include delirium, brain inflammation, stroke, and nerve damage.”

“In May, scientists in China reported in Nature that bat organoids could be infected with SARS-CoV-2, lending evidence to the idea that the virus originated in bats.”

Potential vaccine using measle vaccination – win-win measles and covid solved – kill two birds with 1 stone – https://www.biorxiv.org/content/10.1101/2020.07.11.198291v1

“we generated measles virus (MeV)-based vaccine candidates expressing the SARS-CoV-2 spike glycoprotein (S). Insertion of the full-length S protein gene in two different MeV genomic positions resulted in modulated S protein expression. The variant with lower S protein expression levels was genetically stable and induced high levels of effective Th1-biased antibody and T cell responses in mice after two immunizations. In addition to neutralizing IgG antibody responses in a protective range, multifunctional CD8+ and CD4+ T cell responses with S protein-specific killing activity were detected. These results are highly encouraging and support further development of MeV-based COVID-19 vaccines.”

To confirm or not to confirm is the question – https://www.fox35orlando.com/news/orlando-health-confirms-state-covid-19-report-has-errors

“Countless labs report 100 percent positivity, which means every single person tested was positive. OX 35 sifted through the report to find local testing sites with high numbers, like Centra Care, where the report showed 83 people were tested and all tested positive. The report also showed that the Orlando Veteran’s Affairs Medical Center had a positivity rate of 76 percent. A spokesperson for the VA said officials are looking into the numbers. NCF Diagnostics has a location in Alachua, which reported 88 percent of tests coming back positive and 98 percent for Orlando Health. How could that be? We investigated these astronomical numbers, contacting every location mentioned. Orlando Health, the only to answer our question, confirmed errors in the report. Its positivity rate is in fact only 9.4 percent, not 98 percent as in the report.”

US still on a tear in terms of confirmation. Brazil leads in death at 733

Florida leads confirmation – no surprise if labs reporting 100% positivity rates….Texas leads in death at 60

TX death was distributed across the state no center location which would not indicate a result of an overwhelmed health system. Confirmations continue to be mainly the same 4 counties.

LA and Maricopa now confirming at over 6% of per capita. Fatality rates still low and not moving much with latest confirmation and deaths.

This week we SHOULD see Houston Trauma System Area overwhelm IF the data is right.

Country view stacked by deaths